臨床酵素学の進歩−血清酵素異常症へのアプローチ(2)

イントロダクション
−血清酵素データの評価−

菅　野　剛　史*
　　　　　　　　　　　　　　　　　　　　　　
Introduction，Appreciation of Plasma Enzyme

Takashi KANNO, MD*

The heterogeneities of tissue enzymes and the enzyme distribution patterns of organs, tissues and plasma have now been established by many findings in various cases and diseases. Based on these precise laboratory data, the fields of clinical enzymology has been developed so as to analyze the very specific pathophysiological state in specific disorders. The characteristics of tumor-producing enzymes and genetically modified enzymes were additionally clarified by advances in molecular technology. Enzyme linked immunoglobulins were newly categorized enzyme abnormalities found in plasma enzymes. Genetical abnormalities of plasma enzymes fully explained the clotting abnormalities, hyper coagulability and hyperlipidemia. Based on these advances, the roles and future of clinical enzymology will be presented shown and discussed in this symposium.
[Rinsho Byori 50 : 563〜565, 2002]

*Vice President of Hamamatsu University, School of Medicine, Hamamatsu 431-3192

【Key Words】clinical enzymology(臨床酵素学)，genetic abnormality(遺伝的異常)，enzyme linked immu-noglobulin(酵素結合性免疫グロブリン)，plasma enzyme(血漿酵素)

*浜松医科大学・副学長(〒431-3192 浜松市半田山1-20-1)