血液疾患患者における血液検査のデルタチェック法( I )
−検体取違い検出のための有用性の再検討−
大 原 智 子*1 伊 東 紘 一*1
Revisited Univariate Delta Check Method for Hematologic Laboratories(I)
−Usefulness for Detection of Specimen Mix-up in Patients with Hematologic Disorders−
Tomoko OHARA*1 and Kouichi ITOH*1
We evaluated the delta check method for hematologic laboratories to detect
specimen mix-up. We selected 271 patients with hematologic disorders and
two types of investigation were conducted. The first investigation comprised
statistical analysis, while the second involved evaluation of the procedure.
From parameters of white blood cell, red blood cell, hemoglobin, hematocrit,
mean corpuscular volume(MCV), mean corpuscular hemoglobin(MCH), mean corpuscular
hemoglobin concentration(MCHC), and platelets, MCV was considered to represent
the best single marker to detect artificial mix-up. About 98% of MCV delta
values from one patient were within 3 fl. Conversely, 40% of MCV delta
values in artificial mix-ups exceed 10 fl. No correlations between time
interval and MCV delta values were detected. However, some cases were observed
in which MCV delta values changed markedly over a short period of time
even though the samples originated from one patient. In conclusion, we
recommend investigation for specimen mix-up in cases where MCV delta values
exceed 4 fl.
[Rinsho Byori 50 : 1072〜1075, 2002]
*1Department of Clinical Laboratory Medicine, Jichi Medical School, Kawachi-gun, Tochigi-pref. 329-0498
【Key Words】delta check method(デルタチェック法)，laboratory mistake(検査過誤)，hematologic
disorder(血液疾患)，mean corpuscular volume：MCV(平均赤血球容積)
受付2002年4月22日・受理2002年10月23日
*1自治医科大学臨床検査医学(〒329-0498 栃木県河内郡南河内町薬師寺3311-1)