原著

血液疾患患者における血液検査のデルタチェック法( II )
−同一患者における MCV の著明な変動原因−

大 原 智 子*1 伊 東 紘 一*1
                      
Revisited Univariate Delta Check Method for Hematologic Laboratories(II)
−Causes of Marked MCV Change in Identical Patients with Hematologic Disorder−

Tomoko OHARA*1 and Kouichi ITOH*1

We have identified causative factors contributing to marked mean corpuscular volume(MCV) change. We selected 38 patients who demonstrated changes in MCV of ≧10 fl within less than 30 days. Of the 38 patients, 27 had received blood transfusions and 6 had undergone allogeneic bone marrow transplantation within the previous 2 months. No definitive cause was detected in 5 patients. In conclusion, blood transfusion and bone marrow transplantation can result in substantial MCV change in a short time and can represent confounding factors for the MCV delta check method.
[Rinsho Byori 50 : 1076〜1078, 2002]

*1Department of Clinical Laboratory Medicine, Jichi Medical School, Kawachi-gun, Tochigi-pref. 329-0498

【Key Words】delta check(デルタチェック),specimen mix-up(検体取違い),mean corpuscular volume:MCV(平均赤血球容積),blood transfusion(輸血),bone marrow transplantation(骨髄移植)

受付2002年4月22日・受理2002年10月23日
*1自治医科大学臨床検査医学(〒329-0498 栃木県河内郡南河内町薬師寺3311-1)