診断検査についてのエビデンスの吟味と利用
古 川 壽 亮*
Critical Appraisal of Evidence on Diagnostic Tests
Toshiaki FURUKAWA, MD*
The article explains the use of stratum-specific likelihood ratios(SSLRs)
and the use of a checklist for critically appraising articles on diagnostic
tests. The author recommends the use of SSLRs over sensitivity/specificity
when evaluating the test characteristics of a given test, because the former
retains as much information as possible of the test. Critical appraisal
of a diagnostic test forms a part of the practice of evidence-based medicine(EBM).
The particular importance of paying attention to work-up bias and spectrum
bias when evaluating a diagnostic test is emphasized. It is hoped that
future studies in laboratory medicine will follow these guidelines.
[Rinsho Byori 51 : 19～23, 2003]
*Department of Psychiatry, Nagoya City University, Medical School, Nagoya 467-8601
【Key Words】EBM，validity(妥当性)，reliability(信頼性)，diagnostic test(診断検査)，stratum-specific likelihood ratio(層別尤度比)
*名古屋市立大学大学院医学研究科精神･認知･行動医学分野(〒467-8601 名古屋市瑞穂区瑞穂町川澄1)
E-mail :furukawa@med.nagoya-cu.ac.jp