[Rinsho Byori 51 : 770〜775, 2003]

Study on Blood Rheology Measured by MC-FAN

Koji SEKI*1, Hiroyuki SUMINO, MD, PhD*2 and Masami MURAKAMI, MD, PhD*3

We investigated the effects of various factors on blood rheology, which was evaluated by the passage time of heparinized whole blood using MC-FAN(Micro Channel array Flow ANalyzer). The time for 100m l of whole blood to pass through a microchannel array(Bloody 6-7) was determined. Each passage time was corrected by the saline passage time determined just before the measurement of sample blood. Our results suggest that blood rheology measured by MC-FAN is related to aging, body weight, body mass index and serum lipid parameters(total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglyceride). These results suggest that MC-FAN is useful to analyze blood rheology in pathophysiological conditions.

*1Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi 371-8511