臨床生理検査の最先端(5)

非努力性呼吸生理検査

川　本　　　仁*1　神　辺　眞　之*2
　　　　　　　　　　　　　　　　　　　　　　
Effort-Independent Pulmonary Function Tests

Hitoshi KAWAMOTO, MD*1 and Masayuki KAMBE, MD*2

Many pulmonary function tests require forced expiration, and the precision of the tests depends on the effort of the subjects. In elderly people, the reproducibility of test results may be inadequate because of insufficiency of the subjects’ effort, and the diagnosis of COPD, which is frequently observed in elderly people, is often difficult. To improve the accuracy of the diagnosis, pulmonary function tests that do not require effort are needed. In this study, effortless pulmonary function tests(examinations of the cardiogenic oscillation, negative expiratory pressure, exhaled temperature, and exhaled breath condensate), the application of which to various respiratory disorders(i.e., sleep apnea syndrome, COPD, bronchial asthma) is attempted, are presented.
[Rinsho Byori 51 : 782〜789, 2003]

*1Department of Clinical Laboratory Medicine, Hiroshima University, Graduate School of Biomedical Science, Hiroshima 734-8554

【Key Words】effort-independent pulmonary function tests(非努力性呼吸生理検査法)，cardiogenic oscillation(心原性脈波)，negative expiratory pressure method(NEP 法)，exhaled temperature(呼気温度)，exhaled breath condensate(呼気液化物)

*1,2広島大学大学院医歯薬学総合研究科病態臨床検査医学(〒734-8554 広島市南区霞1-2-3)

E-mail :hitoship@hiroshima-u.ac.jp