最近の臨床血液領域の話題と臨床検査(2)

新 WHO 分類における
悪性リンパ腫・白血病の考え方

菊　池　昌　弘*
　　　　　　　　　　　　　　　　　　　　　　
Malignant Lymphoma and Leukemia Concepts in New WHO Classification

Masahiro KIKUCHI, MD*

The new WHO classification is based on the principles of REAL classification of lymphoma and expands to myeloid, mast cell and histiocytic/dendritic neoplasms. The distinct diseases are defined according to a combination of morphology, immunophenotype, genetic features, and clinical syndromes, and the cell origin is postulated. Lymphatic leukemia is included in lymphoma. The lymphoid malignancies are grouped into B cell lymphoma, T/NK cell lymphoma and Hodgkin lymphoma, and the myeloid neoplasm are grouped into 4 categories; chronic myeloproliferative diseases(chronic myelogenous leukemia, polycythemia vera, chronic idiopathic myelofibrosis, essential thrombocythemia etc.), myelodysplastic/myeloproliferative diseases(chronic myelomonocytic leukemia, juvenile myelomonocytic leukemia etc.), myelodysplastic diseases(perfactory anemia, refractory anemia with ringed sideroblasts etc.) and acute myeloid leukemia.
[Rinsho Byori 51 : 820〜824, 2003 ]

*Department of Pathology, School of Medicine, Fukuoka University, Fukuoka 814-0180

【Key Words】WHO classification(WHO 分類)，lymphoma(リンパ腫)，myeloid leukemia(骨髄性白血病)

*福岡大学医学部病理(〒814-0180 福岡市城南区七隈7-45-1)

E-mail :masakiku@fukuoka-u.ac.jp